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- A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival.
Singh A, Greninger P, Rhodes D, Koopman L, Violette S, Bardeesy N, Settleman J.
Cancer Cell. 2009 Jun 2;15(6):489-500. Pubmed
- AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.
Rhodes DR, Ateeq B, Cao Q, Tomlins SA, Mehra R, Laxman B, Kalyana-Sundaram S, Lonigro RJ, Helgeson BE, Bhojani MS, Rehemtulla A, Kleer CG, Hayes DF, Lucas PC, Varambally S, Chinnaiyan AM.
Proc Natl Acad Sci U S A. 2009 Jun 1. [Epub ahead of print]. Pubmed
- Exploring clinical associations using ‘-omics’ based enrichment analyses.
Hanauer DA, Rhodes DR, Chinnaiyan AM.
PLoS ONE. 2009;4(4):e5203. Epub 2009 Apr 13. Pubmed
- Coactivator Function Defines the Active Estrogen Receptor-{alpha} Cistrome.
Lupien M, Eeckhoute J, Meyer CA, Krum SA, Rhodes DR, Liu XS, Brown M.
Mol Cell Biol. 2009 Apr 13. [Epub ahead of print]
Pubmed
- The role of SPINK1 in ETS rearrangement-negative prostate cancers.
Tomlins SA, Rhodes DR, Yu J, Varambally S, Mehra R, Perner S, Demichelis F, Helgeson BE, Laxman B, Morris DS, Cao Q, Cao X, Andrén O, Fall K, Johnson L, Wei JT, Shah RB, Al-Ahmadie H, Eastham JA, Eggener SE, Fine SW, Hotakainen K, Stenman UH, Tsodikov A, Gerald WL, Lilja H, Reuter VE, Kantoff PW, Scardino PT, Rubin MA, Bjartell AS, Chinnaiyan AM.
Cancer Cell. 2008 Jun;13(6):519-28.
Pubmed
- Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.
Setlur SR, Mertz KD, Hoshida Y, Demichelis F, Lupien M, Perner S, Sboner A, Pawitan Y, Andrén O, Johnson LA, Tang J, Adami HO, Calza S, Chinnaiyan AM, Rhodes D, Tomlins S, Fall K, Mucci LA, Kantoff PW, Stampfer MJ, Andersson SO, Varenhorst E, Johansson JE, Brown M, Golub TR, Rubin MA.
J Natl Cancer Inst. 2008 Jun 4;100(11):815-25. Epub 2008 May 27. Pubmed
- A polycomb repression signature in metastatic prostate cancer predicts cancer outcome.
Yu J, Yu J, Rhodes DR, Tomlins SA, Cao X, Chen G, Mehra R, Wang X, Ghosh D, Shah RB, Varambally S, Pienta KJ, Chinnaiyan AM.
Cancer Res. 2007 Nov 15;67(22):10657-63. Pubmed
- Identifying significant associations using free text problem summary lists in a clinical data repository.
Hanauer DA, Rhodes DR, Chinnaiyan AM.
AMIA Annu Symp Proc. 2007 Oct 11:968. Pubmed
- Molecular concepts analysis links tumors, pathways, mechanisms, and drugs.
Rhodes DR, Kalyana-Sundaram S, Tomlins SA, Mahavisno V, Kasper N, Varambally R, Barrette TR, Ghosh D, Varambally S, Chinnaiyan AM.
Neoplasia. 2007 May;9(5):443-54. Pubmed
- Integrating biomedical knowledge to model pathways of prostate cancer progression.
Morris DS, Tomlins SA, Rhodes DR, Mehra R, Shah RB, Chinnaiyan AM.
Cell Cycle . 2007 May;6(10):1177-87. Pubmed
- Oncomine 3.0: genes, pathways, and
networks in a collection of 18,000
cancer gene expression profiles.
Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Varmbally R, Yu J, Briggs BB, Barrette TR, Anstett MJ, Kincaid-Beal C, Kulkarni P, Varambally S, Ghosh D, Chinnaiyan AM.
Neoplasia. 2007 Feb;9(2):166-80. Pubmed
- Bioinformatics approaches in the study of cancer.
Hanauer DA, Rhodes DR, Sinha-Kumar C,
Chinnaiyan AM.
Curr Mol Med. 2007 Feb;7(1):133-41. Review. Pubmed
- Integrative molecular concept modeling of prostate cancer progression.
Scott A Tomlins, Rohit Mehra, Daniel R Rhodes, Xuhong Cao, Lei Wang, Saravana M Dhanasekaran, Shanker Kalyana-Sundaram, John T Wei, Mark A Rubin, Kenneth J Pienta, Rajal B Shah & Arul M Chinnaiyan.
Nature Genetics 2007 Jan.; 39, 41 - 51 Pubmed
- Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation.
Giordano TJ, Au AYM, Kuick R, Thomas DG, Rhodes DR, Wilhelm KG, Vinco M, Misek DE, Sanders D, Zhu ZW, Ciampi R, Hanash S, Chinnaiyan A, Clifton-Bligh RJ, Robinson BG, Nikiforov YE, Koenig RJ.
Clinical Cancer Research 2006 Apr 1;12(7 Pt 1):1983-93. Pubmed
- TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer.
Tomlins SA, Mehra R, Rhodes DR, Smith LR, Roulston D, Helgeson BE, Cao X, Wei JT, Rubin MA, Shah RB, Chinnaiyan AM.
Cancer Res. 2006 Apr 1;66(7):3396-400. Pubmed
- Whole transcriptome amplification for gene expression profiling and development of molecular archives.
Tomlins SA, Mehra R, Rhodes DR, Shah RB, Rubin MA, Bruening E, Makarov V, Chinnaiyan AM.
Neoplasia. 2006 Feb;8(2):153-62. Pubmed
- Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer.
Fu Z, Kitagawa Y, Shen R, Shah R, Mehra R, Rhodes D, Keller PJ, Mizokami A, Dunn R, Chinnaiyan AM, Yao Z, Keller ET.
Prostate. 2006 Feb 15;66(3):248-56. Pubmed
- Integrative genomic and proteomic
analysis of prostate cancer reveals signatures of metastatic progression.
Varambally S, Yu JJ, Laxman B, Rhodes DR, Mehra R, Tomlins SA, Shah RB, Chandran U, Monzon FA, Becich MJ, Wei JT, Pienta KJ, Ghosh D, Rubin MA, Chinnaiyan AM.
Cancer Cell. 2005 Nov;8(5):393-406. Pubmed
- Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate
cancer.
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, Pienta KJ, Rubin MA, Chinnaiyan AM.
Science 2005 Oct 28;310(5748):644-8. Pubmed
- Probabilistic model of the human protein-protein interaction network.
Rhodes DR, Tomlins SA, Varambally S, Mahavisno V, Barrette T, Kalyana-Sundaram S, Ghosh D, Pandey A, Chinnaiyan AM.
Nat Biotechnology. 2005 Aug; 23(8):951-9 Pubmed
- Integrative analysis of the cancer transcriptome.
Rhodes DR, Chinnaiyan AM.
Nat Genet. 2005 Jun;37 Suppl:S31-7. Review. Pubmed
- Mining for regulatory programs in the cancer transcriptome.
Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Barrette TR, Ghosh D, Chinnaiyan AM.
Nat Genet. 2005 Jun; 37(6):579-83. Pubmed
- Large-Scale Meta-Analysis of Cancer Microarray Data Identifies Common Transcriptional Profiles of Neoplastic Transformation and Progression.
Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM.
PNAS 2004 Jun 22;101(25):9309-14. Pubmed
- Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer.
Rubin MA, Varambally S, Beroukhim R, Tomlins SA, Rhodes DR, Paris PL, Hofer MD, Storz-Schweizer M, Kuefer R, Fletcher JA, Hsi BL, Byrne JA, Pienta KJ, Collins C, Sellers WR, Chinnaiyan AM.
Cancer Res. 2004 Jun; 64 (11): 3814-3822. Pubmed
- Bioinformatics strategies for translating genome-wide expression analyses into clinically useful cancer markers.
Rhodes DR, Chinnaiyan AM.
Ann N Y Acad Sci. 2004 May;1020:32-40. Review. Pubmed
- ONCOMINE: A Cancer Microarray Database and Data-Mining Platform.
Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM.
Neoplasia 2004 Jan-Feb; 6(1):1-6 Pubmed
- Humoral immune response to alpha-methylacyl-CoA racemase and prostate cancer.
Sreekumar A, Laxman B, Rhodes DR, Bhagavathula S, Harwood J, Giacherio D, Ghosh D, Sanda MG, Rubin MA, Chinnaiyan AM.
J Natl Cancer Inst. 2004 Jun 2;96(11):834-43. Erratum in: J Natl Cancer Inst. 2004 Jul 21;96(14):1112. Pubmed
- Prostate cancer biomarkers: a current perspective.
Kumar-Sinha C, Rhodes DR, Yu J, Chinnaiyan AM.
Expert Rev Mol Diagn. 2003 Jul;3(4):459-70. Review. Pubmed
- Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer.
Rhodes DR, Sanda MG, Otte AP, Chinnaiyan AM, Rubin MA.
J Natl Cancer Inst. 2003 May 7;95(9):661-8. Pubmed
- Dysregulation of the annexin family protein family is associated with prostate cancer progression.
Xin W, Rhodes DR, Ingold C, Chinnaiyan AM, Rubin MA.
Am J Pathol. 2003 Jan;162(1):255-61. Pubmed
- DNA microarrays: implications for clinical medicine.
Rhodes DR, Chinnaiyan AM.
J Invest Surg. 2002 Sep-Oct;15(5):275-9. Review. Pubmed
- Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer.
Rhodes DR, Barrette TR, Rubin MA, Ghosh D, Chinnaiyan AM.
Cancer Res. 2002 Aug 1;62(15):4427-33. Pubmed
- CIT: identification of differentially expressed clusters of genes from microarray data.
Rhodes DR, Miller JC, Haab BB, Furge KA.
Bioinformatics. 2002 Jan;18(1):205-6. Pubmed
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