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publications

  1. A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival.
    Singh A, Greninger P, Rhodes D, Koopman L, Violette S, Bardeesy N, Settleman J.
    Cancer Cell. 2009 Jun 2;15(6):489-500. linkPubmed
  2. AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.
    Rhodes DR, Ateeq B, Cao Q, Tomlins SA, Mehra R, Laxman B, Kalyana-Sundaram S, Lonigro RJ, Helgeson BE, Bhojani MS, Rehemtulla A, Kleer CG, Hayes DF, Lucas PC, Varambally S, Chinnaiyan AM.
    Proc Natl Acad Sci U S A. 2009 Jun 1. [Epub ahead of print]. linkPubmed
  3. Exploring clinical associations using ‘-omics’ based enrichment analyses.
    Hanauer DA, Rhodes DR, Chinnaiyan AM.
    PLoS ONE. 2009;4(4):e5203. Epub 2009 Apr 13. linkPubmed
  4. Coactivator Function Defines the Active Estrogen Receptor-{alpha} Cistrome.
    Lupien M, Eeckhoute J, Meyer CA, Krum SA, Rhodes DR, Liu XS, Brown M.
    Mol Cell Biol. 2009 Apr 13. [Epub ahead of print] linkPubmed
  5. The role of SPINK1 in ETS rearrangement-negative prostate cancers.
    Tomlins SA, Rhodes DR, Yu J, Varambally S, Mehra R, Perner S, Demichelis F, Helgeson BE, Laxman B, Morris DS, Cao Q, Cao X, Andrén O, Fall K, Johnson L, Wei JT, Shah RB, Al-Ahmadie H, Eastham JA, Eggener SE, Fine SW, Hotakainen K, Stenman UH, Tsodikov A, Gerald WL, Lilja H, Reuter VE, Kantoff PW, Scardino PT, Rubin MA, Bjartell AS, Chinnaiyan AM.
    Cancer Cell. 2008 Jun;13(6):519-28. linkPubmed
  6. Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.
    Setlur SR, Mertz KD, Hoshida Y, Demichelis F, Lupien M, Perner S, Sboner A, Pawitan Y, Andrén O, Johnson LA, Tang J, Adami HO, Calza S, Chinnaiyan AM, Rhodes D, Tomlins S, Fall K, Mucci LA, Kantoff PW, Stampfer MJ, Andersson SO, Varenhorst E, Johansson JE, Brown M, Golub TR, Rubin MA.
    J Natl Cancer Inst. 2008 Jun 4;100(11):815-25. Epub 2008 May 27. linkPubmed
  7. A polycomb repression signature in metastatic prostate cancer predicts cancer outcome.
    Yu J, Yu J, Rhodes DR, Tomlins SA, Cao X, Chen G, Mehra R, Wang X, Ghosh D, Shah RB, Varambally S, Pienta KJ, Chinnaiyan AM.
    Cancer Res. 2007 Nov 15;67(22):10657-63. linkPubmed
  8. Identifying significant associations using free text problem summary lists in a clinical data repository.
    Hanauer DA, Rhodes DR, Chinnaiyan AM.
    AMIA Annu Symp Proc. 2007 Oct 11:968.linkPubmed
  9. Molecular concepts analysis links tumors, pathways, mechanisms, and drugs.
    Rhodes DR, Kalyana-Sundaram S, Tomlins SA, Mahavisno V, Kasper N, Varambally R, Barrette TR, Ghosh D, Varambally S, Chinnaiyan AM.
    Neoplasia. 2007 May;9(5):443-54. linkPubmed
  10. Integrating biomedical knowledge to model pathways of prostate cancer progression.
    Morris DS, Tomlins SA, Rhodes DR, Mehra R, Shah RB, Chinnaiyan AM.
    Cell Cycle . 2007 May;6(10):1177-87. linkPubmed
  11. Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles.
    Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Varmbally R, Yu J, Briggs BB, Barrette TR, Anstett MJ, Kincaid-Beal C, Kulkarni P, Varambally S, Ghosh D, Chinnaiyan AM.
    Neoplasia. 2007 Feb;9(2):166-80. linkPubmed
  12. Bioinformatics approaches in the study of cancer.
    Hanauer DA, Rhodes DR, Sinha-Kumar C, Chinnaiyan AM.
    Curr Mol Med. 2007 Feb;7(1):133-41. Review. linkPubmed
  13. Integrative molecular concept modeling of prostate cancer progression.
    Scott A Tomlins, Rohit Mehra, Daniel R Rhodes, Xuhong Cao, Lei Wang, Saravana M Dhanasekaran, Shanker Kalyana-Sundaram, John T Wei, Mark A Rubin, Kenneth J Pienta, Rajal B Shah & Arul M Chinnaiyan.
    Nature Genetics 2007 Jan.; 39, 41 - 51 linkPubmed
  14. Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation.
    Giordano TJ, Au AYM, Kuick R, Thomas DG, Rhodes DR, Wilhelm KG, Vinco M, Misek DE, Sanders D, Zhu ZW, Ciampi R, Hanash S, Chinnaiyan A, Clifton-Bligh RJ, Robinson BG, Nikiforov YE, Koenig RJ.
    Clinical Cancer Research 2006 Apr 1;12(7 Pt 1):1983-93. linkPubmed
  15. TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer.
    Tomlins SA, Mehra R, Rhodes DR, Smith LR, Roulston D, Helgeson BE, Cao X, Wei JT, Rubin MA, Shah RB, Chinnaiyan AM.
    Cancer Res. 2006 Apr 1;66(7):3396-400. linkPubmed
  16. Whole transcriptome amplification for gene expression profiling and development of molecular archives.
    Tomlins SA, Mehra R, Rhodes DR, Shah RB, Rubin MA, Bruening E, Makarov V, Chinnaiyan AM.
    Neoplasia. 2006 Feb;8(2):153-62. linkPubmed
  17. Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer.
    Fu Z, Kitagawa Y, Shen R, Shah R, Mehra R, Rhodes D, Keller PJ, Mizokami A, Dunn R, Chinnaiyan AM, Yao Z, Keller ET.
    Prostate. 2006 Feb 15;66(3):248-56. linkPubmed
  18. Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression.
    Varambally S, Yu JJ, Laxman B, Rhodes DR, Mehra R, Tomlins SA, Shah RB, Chandran U, Monzon FA, Becich MJ, Wei JT, Pienta KJ, Ghosh D, Rubin MA, Chinnaiyan AM.
    Cancer Cell. 2005 Nov;8(5):393-406. linkPubmed
  19. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
    Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, Pienta KJ, Rubin MA, Chinnaiyan AM.
    Science 2005 Oct 28;310(5748):644-8. linkPubmed
  20. Probabilistic model of the human protein-protein interaction network.
    Rhodes DR, Tomlins SA, Varambally S, Mahavisno V, Barrette T, Kalyana-Sundaram S, Ghosh D, Pandey A, Chinnaiyan AM.
    Nat Biotechnology. 2005 Aug; 23(8):951-9 linkPubmed
  21. Integrative analysis of the cancer transcriptome.
    Rhodes DR, Chinnaiyan AM.
    Nat Genet. 2005 Jun;37 Suppl:S31-7. Review. linkPubmed
  22. Mining for regulatory programs in the cancer transcriptome.
    Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Barrette TR, Ghosh D, Chinnaiyan AM.
    Nat Genet. 2005 Jun; 37(6):579-83. linkPubmed
  23. Large-Scale Meta-Analysis of Cancer Microarray Data Identifies Common Transcriptional Profiles of Neoplastic Transformation and Progression.
    Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM.
    PNAS 2004 Jun 22;101(25):9309-14. linkPubmed
  24. Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer.
    Rubin MA, Varambally S, Beroukhim R, Tomlins SA, Rhodes DR, Paris PL, Hofer MD, Storz-Schweizer M, Kuefer R, Fletcher JA, Hsi BL, Byrne JA, Pienta KJ, Collins C, Sellers WR, Chinnaiyan AM.
    Cancer Res. 2004 Jun; 64 (11): 3814-3822. linkPubmed
  25. Bioinformatics strategies for translating genome-wide expression analyses into clinically useful cancer markers.
    Rhodes DR, Chinnaiyan AM.
    Ann N Y Acad Sci. 2004 May;1020:32-40. Review. linkPubmed
  26. ONCOMINE: A Cancer Microarray Database and Data-Mining Platform.
    Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM.
    Neoplasia 2004 Jan-Feb; 6(1):1-6 linkPubmed
  27. Humoral immune response to alpha-methylacyl-CoA racemase and prostate cancer.
    Sreekumar A, Laxman B, Rhodes DR, Bhagavathula S, Harwood J, Giacherio D, Ghosh D, Sanda MG, Rubin MA, Chinnaiyan AM.
    J Natl Cancer Inst. 2004 Jun 2;96(11):834-43. Erratum in: J Natl Cancer Inst. 2004 Jul 21;96(14):1112. linkPubmed
  28. Prostate cancer biomarkers: a current perspective.
    Kumar-Sinha C, Rhodes DR, Yu J, Chinnaiyan AM.
    Expert Rev Mol Diagn. 2003 Jul;3(4):459-70. Review. linkPubmed
  29. Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer.
    Rhodes DR, Sanda MG, Otte AP, Chinnaiyan AM, Rubin MA.
    J Natl Cancer Inst. 2003 May 7;95(9):661-8. linkPubmed
  30. Dysregulation of the annexin family protein family is associated with prostate cancer progression.
    Xin W, Rhodes DR, Ingold C, Chinnaiyan AM, Rubin MA.
    Am J Pathol. 2003 Jan;162(1):255-61. linkPubmed
  31. DNA microarrays: implications for clinical medicine.
    Rhodes DR, Chinnaiyan AM.
    J Invest Surg. 2002 Sep-Oct;15(5):275-9. Review. linkPubmed
  32. Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer.
    Rhodes DR, Barrette TR, Rubin MA, Ghosh D, Chinnaiyan AM.
    Cancer Res. 2002 Aug 1;62(15):4427-33. linkPubmed
  33. CIT: identification of differentially expressed clusters of genes from microarray data.
    Rhodes DR, Miller JC, Haab BB, Furge KA.
    Bioinformatics. 2002 Jan;18(1):205-6. linkPubmed

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