Compendia Bioscience announces the addition of 33 highly curated data sets to the Oncomine database. Nearly 50% of these include data not found in GEO. + includes data not found in GEO
includes treatment response or drug sensitvity data
New Datasets
Bittner_Cervix
Samples: 36
Expression Project for Oncology (expO) - Cervix Samples
Analyses: 6
Bittner_Prostate
Samples: 60
Expression Project for Oncology (expO) - Prostate Samples
Analyses: 6
Bittner_Sarcoma
Samples: 77
Expression Project for Oncology (expO) - Sarcoma Samples
Analyses: 14
Bittner_Thyroid
Samples: 33
Expression Project for Oncology (expO) - Thyroid Samples
Analyses: 3
Boersma_Breast+
Samples: 95
A stromal gene signature associated with inflammatory breast cancer.
Analyses: 9
Int J Cancer
PMID: 17999412
Bowtell_Ovarian
Samples: 295
Expression profile of ovarian tumour samples
Analyses: 6
Chin_Breast_2+
Samples: 220
High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer.
Analyses: 7
Genome Biol
PMID: 17925008
Finak_Breast
Samples: 59
Stromal gene expression predicts clinical outcome in breast cancer.
Analyses: 8
Nat Med
PMID: 18438415
Frank_Leukemia
Samples: 45
Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients.
Analyses: 1
Leukemia
PMID: 16728981
Harada_Pancreas+
Samples: 28
Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays.
Analyses: 4
Oncogene
PMID: 17952125
Heller_CellLine
Samples: 24
Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.
Analyses: 9
Cancer Res
PMID: 18172295
Jais_Lymphoma
Samples: 53
The expression of 16 genes related to the cell of origin and immune response predicts survival in elderly patients with diffuse large B-cell lymphoma treated with CHOP and rituximab.
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Analyses: 7
Pigment Cell Res
PMID: 17516929
Karnoub_Breast
Samples: 22
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis.
Analyses: 1
Nature
PMID: 17914389
Khambata-Ford_Colon+
Samples: 80
Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab.
Analyses: 6
J Clin Oncol
PMID: 17664471
Ki_Colon+
Samples: 123
Whole genome analysis for liver metastasis gene signatures in colorectal cancer.
Analyses: 3
Int J Cancer
PMID: 17640062
Kim_Lung
Samples: 138
Prediction of Recurrence-Free Survival in Postoperative NSCLC Patients—a Useful Prospective Clinical Practice
Analyses: 2
Liu_Prostate
Samples: 57
Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells.
Analyses: 3
Cancer Res
PMID: 16618720
Lombardi_CellLine+
Samples: 23
Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease.
Analyses: 5
Genes Chromosomes Cancer
PMID: 17171682
Meani_Leukemia
Samples: 20
Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.
Analyses: 3
Oncogene
PMID: 15735696
Miller_Breast_2
Samples: 116
Changes in breast cancer transcriptional profiles after treatment with the aromatase inhibitor, letrozole.
Analyses: 1
Pharmacogenet Genomics
PMID: 17885619
Rae_CellLine
Samples: 12
GREB1 is a critical regulator of hormone dependent breast cancer growth.
Analyses: 3
Breast Cancer Res Treat
PMID: 15986123
Santegoets_Vulva+
Samples: 19
HPV related VIN: highly proliferative and diminished responsiveness to extracellular signals.
Analyses: 3
Int J Cancer
PMID: 17471573
Schaefer_Sarcoma+
Samples: 37
Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy.
Analyses: 10
Eur J Cancer
PMID: 18294840
Shames_CellLine+
Samples: 42
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies
Analyses: 3
PLoS Med
PMID: 17194187
Soulier_Leukemia+
Samples: 104
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).
Analyses: 8
Blood
PMID: 15774621
Su_Lung
Samples: 66
Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme.
Analyses: 1
BMC Genomics
PMID: 17540040
Tooker_CellLine
Samples: 20
Bexarotene (LGD1069, Targretin), a selective retinoid X receptor agonist, prevents and reverses gemcitabine resistance in NSCLC cells by modulating gene amplification.
Analyses: 4
Cancer Res
PMID: 17483357
Wang_CellLine+
Samples: 32
Identification of candidate predictive and surrogate molecular markers for dasatinib in prostate cancer: rationale for patient selection and efficacy monitoring.
Analyses: 4
Genome Biol
PMID: 18047674
Wooster_CellLine+
Samples: 318
Transcript profiling of cancer cell line panel
Analyses: 23
Wurmbach_Liver+
Samples: 75
Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma.
Analyses: 7
Hepatology
PMID: 17393520
Xu_Melanoma+
Samples: 154
Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases.
Analyses: 16
Mol Cancer Res
PMID: 18505921
Updated Datasets
These studies have been updated with additional samples or sample parameters based on the most recent data available. All have additional analyses.
Bittner_Breast
Samples: 336
Expression Project for Oncology (expO) - Breast Samples
Analyses: 11
Bittner_Colon
Samples: 373
Expression Project for Oncology (expO) - Colon Samples
Analyses: 13
Bittner_Endometrium
Samples: 177
Expression Project for Oncology (expO) - Endometrium Samples
Analyses: 10
Bittner_Lung
Samples: 109
Expression Project for Oncology (expO) - Lung Samples
Analyses: 11
Bittner_Melanoma+
Samples: 31
Molecular classification of cutaneous malignant melanoma by gene expression profiling.
Analyses: 3
Nature
PMID: 10952317
Bittner_Ovarian
Samples: 241
Expression Project for Oncology (expO) - Ovarian Samples
Analyses: 12
Bittner_Renal
Samples: 256
Expression Project for Oncology (expO) - Renal Samples
Analyses: 9
Compendia_CellLine+
Samples: 61
Gene expression signatures associated with chemosensitivity in the NCI-60 cell lines - added mutation analyses
Analyses: 42
Hoek_Melanoma_2+
Samples: 45
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Analyses: 2
Pigment Cell Res
PMID: 16827748
Huang_Breast+
Samples: 89
Gene expression predictors of breast cancer outcomes
Analyses: 9
Lancet
PMID: 12747878
Martinez_Lymphoma+
Samples: 40
The molecular signature of mantle cell lymphoma reveals multiple signals favoring cell survival.