01 OCT 2009
Data Details
Compendia Bioscience announces the addition of 22 carefully curated datasets to the Oncomine database, bringing the total to 501.
Twenty seven percent contain data not found in GEO. Compendia thanks the many study authors who have helped clarify and add valuable supplementary data to these datasets in Oncomine.
Adai CellLine
Samples: 206
Beroukhim Renal +
Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney.
PMID: 19470766
| Cancer Res, 2009 | Samples: 70
Bonnefoi Breast + 
Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial.
PMID: 18024211
| Lancet Oncol, 2007 | Samples: 160
Carver CellLine
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.
PMID: 19396168
| Nat Genet, 2009 | Samples: 4
Connolly CellLine
Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro.
PMID: 19034449
| Cancer Chemother Pharmacol, 2009 | Samples: 18
Dyrskjot Bladder 5
Gene expression signatures predict outcome in non-muscle-invasive bladder carcinoma: a multicenter validation study.
PMID: 17575217
| Clin Cancer Res, 2007 | Samples: 808
Gaspar Colon +
Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis.
PMID: 18403596
| Am J Pathol, 2008 | Samples: 78
Hoeflich Breast
In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models.
PMID: 19567590
| Clin Cancer Res, 2009 | Samples: 30
Hoeflich CellLine (RELOADED)
In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models.
(originally loaded as Januario CellLine)
PMID: 19567590
| Clin Cancer Res, 2009 | Samples: 17
Hoeflich CellLine 2 + (RELOADED)
In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models.
(originally loaded as Januario CellLine 2)
PMID: 19567590
| Clin Cancer Res, 2009 | Samples: 51
Hu Cell Line
Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition.
PMID: 19164467
| Endocrinology, 2009 | Samples: 9
Julka Breast +
A phase II study of sequential neoadjuvant gemcitabine plus doxorubicin followed by gemcitabine plus cisplatin in patients with operable breast cancer: prediction of response using molecular profiling.
PMID: 18382427
| Br J Cancer, 2008 | Samples: 44
Loi Breast
Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade.
PMID: 17401012
| J Clin Oncol, 2007 | Samples: 87
Loi Breast 3
Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen.
PMID: 18498629
| BMC Genomics, 2008 | Samples: 77
Nagashima CellLine
Mutation of epidermal growth factor receptor is associated with MIG6 expression.
PMID: 19674104
| FEBS J, 2009 | Samples: 60
Nickeleit CellLine
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition.
PMID: 18598941
| Cancer Cell, 2008 | Samples: 17
Ohyashiki CellLine
The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1.
PMID: 19298223
| Cancer Sci, 2009 | Samples: 6
Pratilas CellLine
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway.
PMID: 19251651
| Proc Natl Acad Sci U S A, 2009 | Samples: 32
Raab CellLine
Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling.
PMID: 19018094
| Blood, 2009 | Samples: 6
TCGA Brain 2
The Cancer Genome Atlas - Glioblastoma Agilent aCGH data.
PMID: NA
| NA | Samples: 326
TCGA Ovarian 2
The Cancer Genome Atlas - Ovarian Serous Cystadenocarcinoma Agilent aCGH data.
PMID: NA
| NA | Samples: 48
Tothill Ovarian + (RELOADED)
Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome.
(originally loaded as Bowtell Ovarian)
PMID: 18698038
| Clin Cancer Res, 2008| Samples: 295
Wouters Leukemia +
Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome.
PMID: 19171880
| Blood, 2009 | Samples: 526
Yuan CellLine
Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene.
PMID: 19359602
| Circ Res, 2009 | Samples: 6
Yusenko Renal
High-resolution DNA copy number and gene expression analyses distinguish chromophobe renal cell carcinomas and renal oncocytomas.
PMID: 19445733
| BMC Cancer, 2009 | Samples: 67
Zhan Myeloma 2 (RELOADED)
The molecular classification of multiple myeloma.
(added 224 samples to originally loaded dataset)
PMID: 16728703
| Blood, 2006 | Samples: 414
PLEASE NOTE: These datasets have been removed.
1. Leung Gastric (samples duplicated in Chen Gastric)
2. Miller Breast (samples duplicated in Ivshina Breast)
3. Okada Liver (samples duplicated in Iizuka Liver)
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includes treatment response or drug sensitivity data