Data Details

Compendia Bioscience announces the addition of 62 highly curated datasets to the Oncomine database.
+ includes data not found in GEO
includes treatment response or drug sensitvity data

 Albino Brain

Identification of low intratumoral gene expression heterogeneity in neuroblastic tumors by genome-wide expression analysis and game theory.
PMID: 18671248 | ACS, 2008 | Samples: 28

 Almeida CellLine

Multiple end-point analysis reveals cisplatin damage tolerance to be a chemoresistance mechanism in a NSCLC model: Implications for predictive testing.
PMID: 18074354 | Int J Cancer, 2008 | Samples: 6

 Auman Colon

Celecoxib pre-treatment in human colorectal adenocarcinoma patients is associated with gene expression alterations suggestive of diminished cellular proliferation.
PMID: 18653328 | European Journal of Cancer, 2008 | Samples: 23

 Booman Lymphoma

Genomic alterations and gene expression in primary diffuse large B-cell lymphomas of immune-privileged sites: the importance of apoptosis and immunomodulatory pathways.
PMID: 18729069 | J Pathol, 2008 | Samples: 40

 Bruennert Leukemia

Early in vivo changes of the transcriptome in Philadelphia chromosome-positive CD34+ cells from patients with chronic myelogenous leukaemia following imatinib therapy.
PMID: 19052557 | Leukemia, 2008 |Samples: 12

 Burington Myeloma

Tumor cell gene expression changes following short-term In vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma.
PMID: 18676754 | Clin Cancer Res, 2008 |Samples: 229

 Chiang Liver

Focal gains of VEGFA and molecular classification.
PMID: 18701503 | Cancer Res, 2008 | Samples: 91

 Collado CellLine

Tumour biology: senescence in premalignant tumours.
PMID: 16079833 | Nature, 2005 | Samples: 10

 Creighton CellLine 2

Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis.
PMID: 18757322 | J Clin Oncol, 2008 | Samples: 11

 Daigeler Sarcoma +

Heterogeneous in vitro effects of doxorubicin on gene expression in primary human liposarcoma cultures.
PMID: 18959781 | BMC Cancer, 2008 | Samples: 38

 Dairkee Breast 2

Bisphenol A induces a profile of tumor aggressiveness in high-risk cells from breast cancer patients.
PMID: 18381411 | Cancer Res, 2008 | Samples: 24

 Ding Lung +

Somatic mutations affect key pathways in lung adenocarcinoma.
PMID: 18948947 | Nature, 2008 | Samples: 75

 DirectorsChallenge Lung

Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study.
PMID: 18641660 | Nat Med, 2008 | Samples: 443

 Dittmer CellLine

Parathyroid hormone-related protein regulates tumor-relevant genes in breast cancer cells.
PMID: 16551631 | J Biol Chem, 2006 | Samples: 6

 Duggan CellLine

Low pH induces co-ordinate regulation of gene expression in oesophageal cells.
PMID: 16113055 | Carcinogenesis, 2006 | Samples: 10

 Dyrskjot Bladder

Identifying distinct classes of bladder carcinoma using microarrays.
PMID: 12469123 | Nat Genet, 2003 | Samples: 40

 Dyrskjot Bladder 2 +

Identifying distinct classes of bladder carcinoma using microarrays.
PMID: 12469123 | Nat Genet, 2003 | Samples: 31

 Eskandarpour CellLine +

Oncogenic NRAS has multiple effects on the malignant phenotype of human melanoma cells cultured in vitro.
PMID: 18814281 | Int J Cancer, 2009 | Samples: 51

 Gomez CellLine

Human X-Box binding protein-1 confers both estrogen independence and antiestroge resistance in breast cancer cell lines.
PMID: 17660348 | FASEB Journal, 2007 | Samples: 6

 Hughes-Fulford CellLine

Arachidonic acid activates phosphatidylinositol 3-kinase signaling and induces gene expression in prostate cancer.
PMID: 16452198 | Cancer Res, 2006 | Samples: 8

 Janoueix-Lerosey Brain

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma.
PMID: 18923523 | Nature, 2008 | Samples: 64

 Kim CellLine 3

Staufen1 regulates diverse classes of mammalian transcripts.
PMID: 17510634 | EMBO, 2007 | Samples: 6

 Klapper Lymphoma

Molecular profiling of pediatric mature b-cell lymphoma treated in population-based prospective clinical trials.
PMID: 18509088 | Blood, 2008 | Samples: 36

 Kool Brain +

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features.
PMID: 18769486 | PLoS ONE, 2008 | Samples: 62

 + Kuriakose Head-Neck

Selection and validation of differentially expressed genes in head and neck cancer.
PMID: 15170515 | Cell Mol Life Sci, 2004 | Samples: 44

 Landemaine Breast

A six-gene signature predicting breast cancer lung metastasis.
PMID: 18676831 | Cancer Res, 2008 | Samples: 23

 Landi Lung

Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival.
PMID: 18297132 | PLoS ONE, 2008 | Samples: 107

 Lecane CellLine

Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines.
PMID: 16357179 | Cancer Res, 2005 | Samples: 18

 Lenz Lymphoma

Stromal gene signatures in large-B-cell lymphomas.
PMID: 19038878 | N Engl J Med, 2008 | Samples: 414

 Liao Liver

Identification of SOX4 target genes using phylogenetic footprinting-based prediction from expression microarrays suggests that overexpression of SOX4 potentiates metastasis in hepatocellular carcinoma.
PMID: 18504433 | Oncogene, 2008 | Samples: 13

 Lu Breast

Predicting features of breast cancer with gene expression patterns.
PMID: 18297396 | Breast Cancer Res Treat, 2008 | Samples: 129

 Magda CellLine

Motexafin gadolinium disrupts zinc metabolism in human cancer cell lines.
PMID: 15867382 | Cancer Res, 2005 | Samples: 18

 Mellman CellLine

A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs.
PMID: 18288197 | Nature, 2008 | Samples: 9

 Metzeler Leukemia

An 86 probe set gene expression signature predicts survival in cytogenetically normal acute myeloid leukemia.
PMID: 18716133 | Blood, 2008 | Samples: 163

 Metzeler Leukemia 2

An 86 probe set gene expression signature predicts survival in cytogenetically normal acute myeloid leukemia.
PMID: 18716133 | Blood, 2008 | Samples: 79

 Molenaar CellLine

Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma.
PMID: 18413728 | Cancer Res, 2008 | Samples: 13

 Mulligan Myeloma

Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib.
PMID: 17185464 | Blood, 2007 | Samples: 528

 Muthusamy CellLine

Epigenetic silencing of novel tumor suppressors in malignant melanoma.
PMID: 17145863 | Cancer Res, 2006 | Samples: 16

 Nindl Skin

Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling.
PMID: 16893473 | Molecular Cancer, 2006 | Samples: 15

 Patsos CellLine

O-glycan regulation of apoptosis and proliferation in colorectal cancer cell lines.
PMID: 17956354 | Biochemical Society Transactions, 2007 | Samples: 8

 Pramoonjago CellLine

Knockdown of Sox4 expression by RNAi induces apoptosis in ACC3 cells.
PMID: 16636670 | Oncogene, 2006 | Samples: 6

 Raponi Leukemia +

A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia.
PMID: 18160667 | Blood, 2008 | Samples: 34

 Riker Melanoma +

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis.
PMID: 18442402 | BioMed, 2008 | Samples: 87

 Sabates-Bellver Colon

Transcriptome profile of human colorectal adenomas.
PMID: 18171984 | Mol Cancer Res, 2007 | Samples: 64

 Schmidt Breast

The humoral immune system has a key prognostic impact in node-negative breast cancer.
PMID: 18593943 | Cancer Res, 2008 | Samples: 200

 Segara Pancreas +

Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia.
PMID: 15867264 | Clin Cancer Res, 2005 | Samples: 17

 Selga CellLine

Role of Caveoline I, E-Cadherin, Enolast 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells.
PMID: 18694510 | BMC Medical Genomics, 2008 | Samples: 6

 Shang CellLine

Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake.
PMID: 18790743 | Mol Cancer Ther, 2008 | Samples: 8

 Shankavaram CellLine 2

Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study.
PMID: 17339364 | Mol Cancer Ther, 2007 | Samples: 60

 Sorich Leukemia +

In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile.
PMID: 18416598 | PLoS ONE, 2008 | Samples: 161

 Stephan Adrenal

Adrenocortical carcinoma survival rates correlated to genomic copy number variants.
PMID: 18281524 | Mol Cancer Ther, 2008 | Samples: 25

 Stossi CellLine

Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) alpha or ERbeta in human osteosarcoma cells: distinct and common target genes for these receptors.
PMID: 15033914 | Endocrinology, 2004 | Samples: 20

 TCGA Brain

The Cancer Genome Atlas - Glioblastoma Gene Expression Data
Samples: 145

 TCGA Ovarian

The Cancer Genome Atlas - Ovarian Serous Cystadenocarcinoma Gene Expression Data
Samples: 48

  Tse CellLine +

ABT-263: a potent and orally bioavailable bcl-2 family inhibitor.
PMID: 18451170 | Cancer Res, 2008 | Samples: 46

 Wallace Prostate

Tumor immunobiological differences in prostate cancer between African-American and European-American men.
PMID: 18245496 | Cancer Res, 2008 | Samples: 69

 Wang CellLine 2

Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression.
PMID: 17233922 | Molecular Cancer, 2007 | Samples: 12

 Weir Lung

Characterizing the cancer genome in lung adenocarcinoma.
PMID: 17982442 | Nature, 2007 | Samples: 371

 Wonsey CellLine

Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe.
PMID: 15958562 | Cancer Res, 2005 | Samples: 9

 Wooster CellLine 2

SNP profiling of cancer cell line panel
Samples: 338

 Yauch Pancreas

A paracrine requirement for hedgehog signalling in cancer.
PMID: 18754008 | Nature, 2008 | Samples: 8

 Yu Multi-Cancer

A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers.
PMID: 18636107 | PLoS ONE, 2008 | Samples: 341