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17 SEP 2008
LARGE CELL LINE AND PRIMARY TUMOR PANELS, DRUG RESPONSE AND MUTATIONS

For this data release, the Compendia Bioscience team has responded to requests for recently published data as well as enriching current datasets with newly available parameters. The team has worked to bring you 33 highly curated datasets, 3 datasets with additional analyses, and 7 datasets with additional samples. Nearly 50% of the studies in this data release include data not found in GEO. A few highlighted datasets are below and a complete list can be found by clicking on the more link.

  • Wooster_CellLine - 318 cell line samples profiled by GlaxoSmithKline
  • Compendia_CellLine - 59 cell lines from the NCI-60 panel now annotated with mutation data from the Sanger Institute.
  • Frank_Leukemkia - 45 chronic myelogenous leukemia samples with Imatinib Response data
  • Khambata-Ford_Colon - 80 metastatic colon samples with Cetuximab Response and KRAS mutation data
  • Ki_Colon - 123 samples representing colon carcinoma, adjacent normal colon, metastases to liver, and adjacent liver
  • Bowtell_Ovarian - 295 Ovarian Carcinoma samples, representing 4 different subtypes.
  • Chin_Breast_2 - 171 breast cancer samples and 49 breast cancer cell lines analyzed by aCGH
  • Johansson_CellLine - 63 melanoma cell lines with mutation data on genes involved in the MAPK, PI3K, and TP53 pathways
  • Wurmbach_Liver - 75 liver samples representing the progression from normal to hepatocellular carcinoma in HCV positive patients
    more->
  • Data Changes – As part of Compendia’s commitment to improving the curation and annotation of our data, changes may be made to previously released Oncomine datasets. All changes to Oncomine content are documented; a list of all changes is available upon request.  Major changes can be found Here ->.
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