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THE POWER OF THE TOOLS
Power Tools are built on the Oncomine platform and utilize the latest data and analyses. Each application is designed to address questions in the R&D life cycle.
DISCOVERY
DNA Copy Number Browser: Identify focal amplifications and distinguish driver from passenger amplifications/deletions across multiple clinical datasets
Gene Expression Browser: Identify and confirm differential expression in multiple cancer types across multiple independent datasets
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Mutation Browser: Explore frequency of mutation for a specific gene or identify most prevalent mutation in a cancer type
Gene Browser: Identify significant genetic alterations across all cancer types in a single snapshot view with the capability of drilling down to the sample level
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QUESTIONS TO ASK:
- What gene is mostly frequently mutated in glioblastomas and which amino acid changes are recurrent that are predictive of a potential oncogene?
- What novel mutations exist in the latest exon wide high throughput sequencing experiments?
- What focal amplifications are present in 2–3% of lung cancer clinical samples and what cell lines possess similar amplifications to use as models?
- What novel amplifications can be identified in the latest high resolution Agilent experiments from TCGA and Broad Tumorscape data?
- What cancer types show highest level of expression of my target gene in clinical samples and cell lines?
HOW TO GET POWER TOOLS:
Oncomine Power Tools are one way to visualize Oncomine data. First you will need to license Oncomine data and then you can choose the best way to view the data — Oncomine Concepts Edition or Oncomine Power Tools.
Contact us to learn how to access Oncomine Power Tools.
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