9–11 JAN 2012
BIOTECH SHOWCASE
San Francisco, CA

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15 DEC 2011
RESISTANCE IS FUTILE

Drug resistance occurs when a tumor that initially responds to drug treatment becomes resistant, and begins to proliferate even in the presence of the drug. This is thought to occur because while most cells of the tumor are sensitive to the drug, a few cells have mutations that allow them to evade the mechanism of that particular drug…

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Garand, C. et al. An integrative approach to identify YB-1-interacting proteins required for cisplatin resistance in MCF7 and MDA-MB-231 breast cancer cells. Cancer Sci. 2011 Jul;102(7):1410-7.

Crea, F. et al. BMI1 silencing enhances docetaxel activity and impairs antioxidant response in prostate cancer. Int J Cancer. 2011 Apr 15;128(8):1946-54.

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